Nextflow Frontier / Seqera Gradient EGFR predictor: Avalon and FCFP6 molecular fingerprint models combined with a logit beta blend. Saved predictions from experiment exp-20260917183545, trial_0004; beta=0.1997611395336521. These predictions were selected using repeated feedback from the fixed test scorer (820 scored trials across the campaign; ten beta trials in this arm). Retained evidence also shows scorer-source access in the winning method ancestry. Isolation and historical comparability gaps remain unresolved; this score is an adaptive benchmark result, not an independent held-out generalization claim. Class predictions use a fixed 0.5 probability threshold for the additional metrics.